A Case of Hydrocortisone Sodium Succinate (Saxizon®)-Induced Asthma

Yuji Ohashi; Naohika Ando; Toshio Numao; Takao Yamai; Shinji Motojima; Takeshi Fukuda; Ryosuke Ikemori; Sohei Makino

doi:10.11389/jjrs1963.24.1034

A Case of Hydrocortisone Sodium Succinate (Saxizon^®)-Induced Asthma

Yuji Ohashi, Naohika Ando, Toshio Numao, Takao Yamai, Shinji Motojima, Takeshi Fukuda, Ryosuke Ikemori, Sohei Makino

Author information

Keywords: Hydrocortisone sodium succinate, Asprin sensitive asthma, Anaphylaxis-like reaction, Prausnitz-Küstner test

JOURNAL FREE ACCESS

1986 Volume 24 Issue 9 Pages 1034-1038

DOI https://doi.org/10.11389/jjrs1963.24.1034

Details

Abstract

A 32 year-old female patient with bronchial asthma developed an anaphylaxis-like reaction after intravenous injections of Saxizon. Positive inhalation provocation tests were observed with Sulpyrin and Saxizon. Intradermal skin tests revealed positive immediate reactions to Saxizon. Although the Prausnitz-Küstner reaction was positive to Saxizon, RAST was negative.
These results suggest that this patient's immediate hypersensitivity was mediated by IgE antibody against Saxizon.

Corresponding author

Register with J-STAGE for free!