Abstract
Clinical manifestations and prognosis were studied in 554 patients with sarcoidosis diagnosed in Kyoto between 1963 and 1986. The group included a large number of patients in their 20's with BHL alone in whom the disease was detected by health screening. Since many of these patients show spontaneous clearance, steroids are not only unnecessary but are possibly considered to be harmful. Symptomatic patients often showed ocular symptoms. Severe pulmonary fibrosis as reported by European and American authors was observed in only 2.5% of our patients after 5 years observation. It is of profound interest whether such patients will increase in Japan.