The Japanese journal of thoracic diseases
Online ISSN : 1883-471X
Print ISSN : 0301-1542
ISSN-L : 0301-1542
A Case of Subacute Necrotizing Lymphadenitis with Localized Interstitial Pneumonia
Masako TanakaTakafumi YanoYoichiro IchikawaMasaro Kaji
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JOURNAL FREE ACCESS

1990 Volume 28 Issue 9 Pages 1234-1238

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Abstract
A 16-year-old male was admitted with a history of cervical lymph node swelling, high fever, cough and hemosputum. On admission, bilateral cervical lymph nodes swelling and fine crackles in the right lower lung field were noted. A chest X-ray film showed an infiltrative shadow in the right lower lung field and right hilar enlargement. Cervical lymph node biopsy specimens revealed wide areas of necrosis with nuclear debris. Transbronchial lung biopsy showed infiltration of lymphocytes in the interstitium and bronchoalveolar lavage fluid showed increased T-lymphocytes and a decreased T4/T8 ratio. The patient was diagnosed to have subacute necrotizing lymphadenitis with T-lymphocyte alveolitis. Additionally, antinuclear antibodies were positive, and anti HTLV-I antibody was false positive. These findings suggested an immonological abnormality in this case. His cervical lymph node swelling and infiltrative shadow on chest X-ray film improved with steroid therapy. Our case may be the first case of subacute necrotizing lymphadenitis with T-lymphocyte alveolitis.
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© by The Japanese Respiratory Society
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