Abstract
A case was a 58 year old female with chief complaint of bloody sputa. She had a fit of facial frushing several times during eight months.
The chest X-ray revealed an atelectasis with tumorous shadow in the right upper lung field.
A tumor was found in the right main bronchus by bronchoscopy, and right pneumonectomy was performed.
Histologically the tumor was carcinoid. Electronmicroscopically the tumor contained many characteristic serotonin granules of the so-called neurosecretory type, round, electronopaque, with an average diameter about 2000Å, limited by unit membrane in the cytoplasm of light cells or dark cells.
Significant high level of serotonin 666mcg/1 was found in serum, and 5HIAA 33.3mg/24hrs in urine.
After operation, attacks of cramp-like abdominal pain occured frequently, so laparoscope was performed, and was detected metastasis in both lobes of the liver.
