Abstract
In this report, we introduced our project of the extension and the rebuilding of the building of Central Institute of Isotope Science (CIS), Hokkaido University, which has been planned in terms of the present state and the future outlook for the management of CIS. We first fixed a layout of that building and the dose of radioisotope (RI) in the renewed CIS building in consideration of the present usage states, and then carried out a sort of designing of building such as calculation of the wall thickness corresponded to the RI usage dose, arrangement of exhaust and drainage equipments, and so on. Furthermore, we attempted to design the building with an appropriate function for education and safety control of radiation and RI as well as flexibility in response to user's demands on performing a various kind of researches.