Abstract
Many researchers are investigating brain function by using a block paradigm in fMRI measurement.However, time resolution has been limited because the block paradigm employed data collection by consecutive image acquisition after stimulation began. Because of this problem, the evaluation of early brainactivity was not adequate. Therefore, a system that was able to take imaging from a high time dependenceto stimulation in real time was necessary to evaluate early brain activity. It is necessary to obtain controlledimage taking by an MRI device with an external trigger by creating a sequence design in the system controlling stimulation and a sequence designed to achieve the above. The execution of a single paradigm by theoriginally designed sequence thus becomes possible, and arbitrarily setting all processes from stimulationto image taking is possible. It is thought that the practical use of the single paradigm designed by the control system of stimulation enables real-time imaging for stimulation and provides time-dependent data. Fromthis, evaluation of brain activity of the primary motor cortex is possible in the early stage by event-relateddata collection. In addition, "sank," a relative decrement in PO^2 was also an initial stage of BOLD, that is,an initial dip occurs as a transitory signal change by using a single paradigm that synchronizes with thecontrol system of stimulation for the evaluation of early brain activity. Moreover, it is thought that takingimages by a single paradigm that is synchronized with the control system of stimulation is indispensable fortime and spatial elucidation of detailed brain activity, to evaluate hyper brain function. Therefore, the brainactivity in the primary visual cortex at the early stage was clarified in this study by using a single paradigmdesigned to synchronize with the control system of stimulation by single-shot EPI.
