A CASE OF QUADRUPLE PRIMARY CANCER : ADENOSQUAMOUS CARCINOMA OF THE STOMACH AND BLADDER CANCER AFTER OPERATIONS FOR RECTAL AND RENAL CANCERS

Abstract

We report a case of adenosquamous carcinoma of the stomach and bladder cancer after operations for rectal and renal cancers. A 71-year-old male was admitted to our hospital for close exploration of a gastric tumor. Upper gastrointestinal endoscopy and roentogenography revealed a giant lesion of Type 3 cancer extended from the upper body to the angle of the stomach. Preoperative biopsy demonstrated poorly differentiated adenocarcinoma and signet ring cell carcinoma. Total gastrectomy with lymph node dissection was performed. The pathological diagnosis of the tumor was adenosquamous carcinoma with lymph node metastases in stage IIIB (T3 N2 P0 H0 M0 CY0). Adjuvant chemotherapy was performed after the operation for bladder cancer, but multiple liver metastases appeared 6 months after the operation and he died 8 months after the operation. Prognosis was poor in this patient. This case was considered to be relatively rare because of quadruple cancer including adenosquamous carcinoma of the stomach.