A case of a granulosa cell tumor recurred 21 years after the initial surgery which was mimicking a gastric submucosal tumor

Abstract

We report a case of a 70–year–old female who had suffered a metastatic recurrence 21 years after an operation for a granulosa cell tumor. She was admitted to our hospital because of abdominal pain. Abdominal CT scan revealed four solid tumors, one of which was located close to the esophago–gastric junction and diagnosed as gastric submucosal tumor with gastrointestinal endoscopy. These tumors were completely excised and diagnosed histologically as recurred granulosa cell tumor, because they showed the same histological features as those of the resected specimen of an ovarian tumor at another hospital 21 years before admission and immunohistological findings specific for granulosa cell tumor were positive. No recurrence has seen up to now.
The recurrence of granulosa cell tumor after a long course following the first operation is not rare. In the case of a patient with a gastric submucosal tumor or abdominal tumors who has a past history of operation for an ovarian tumor, the metastatic recurrence must be kept in mind.