Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
CLINICAL STUDIES
Gastric cancer in a patient with plummer-vinson syndrome
Hiroki TAKEMOTOSetsujou SHIOTAHiroyuki KISHIMOTOToru HINOHARA
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2008 Volume 69 Issue 3 Pages 548-552

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Abstract
A 62-year-old man with a long-standing history of dysphagia and anemia was admitted to our hospital with symptoms of severe dysphagia and general weakness. Laboratory analysis revealed a typical iron deficiency anemia. Gastrointestinal x-ray and endoscopic examinations showed a membranous stenosis in the upper esophagus, which suggested an esophageal web and a Borrmann type 1 tumor on greater curvature of the gastric body which was proved to be a moderately-differentiated adenocarcinoma by endoscopic biopsy. Under a diagnosis of gastric cancer with Plummer -Vinson syndrome, the patient underwent radical subtotal gastrectomy with D2 nodal dissection. Macroscopically, the resected stomach contained a Borrmann type 1 cancer in the body. Pathological findings demonstrated atrophic change of the gastric mucosa and a lesion of papillary adenocarcinoma. The patient had an uneventful postoperative course, and his dysphagia and iron deficiency anemia have recovered by oral administration of iron therapy.
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© 2008 Japan Surgical Association
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