Abstract
A 54-year-old man with constipation found to have serious sigmoid colon cancer with multiple liver metastatic tumors underwent sigmoidectomy to avoid colon obstruction. Pathological examination of the specimen showed a high nuclear cytoplasmic ratio with increased nuclear chromatin. Immunohistochemical staining showed positive chromogranin A and CD 56, indicating small cell carcinoma. Based on the chemotherapy regimen for small cell lung cancer, we chose CDDP+CPT-11 as first-line therapy, which clearly shrank the multiple liver tumors. After detection of a pelvic tumor 7 months later, we changed the treatment to CDDP+etoposide with radiation. And after the use of hydrochloric acid amurubicin for the regrowth of the hepatic tumor CDDP+CPT-11 was administered again and the patient was put under observation. Small cell carcinoma has dismal prognosis, but different treatments may provide long-term survival while maintaining good quality of life.
