Abstract
An 83-year-old woman who had undergone radical mastectomy with bilateral oophorectomy under the diagnosis of left breast cancer at the age of 45 was seen at the dermatological department in our hospital because of a left cervical tumor. A hard tumor measuring 3 by 4 cm with skin invasion was confirmed at her supraclavicular region. Skin biopsy of the lesion revealed diffusely invasive tumor cells that were positive in immunohistochemical staining with CEA, cytokeratin, estrogen receptor and progesterone receptor. Moreover, blood examination revealed high serum levels of CEA (6.9 ng/ml) and NCC-ST-439 (490.2 U/ml). According to these findings, she was diagnosed as having late recurrence of breast cancer. Hormonal therapy using anastrozole was started and the tumor disappeared 7 months after the beginning of the chemotherapy. Thereafter CR has been kept for more than 8 months. To the best of our knowledge, this case is of the latest recurrent breast cancer reported in the Japanese literature.
