Abstract
We report a rare case of poorly differentiated adenocarcinoma of the duodenum in a 53-year-old man. The patient was admitted to our hospital because of 15kg weight loss in half a year. Barium meal study and gastric endoscopy examination revealed a Borrmann 2 type tumor in the duodenal bulb. Histological diagnosis of the biopsy specimen was adenocarcinoma. After the preoperative examination showed a tumor confined to the duodenal wall but no lymph node metastasis, we performed distal gastrectomy and partial duodenectomy with D2 lymph node dissection. The resected specimen contained a 60×35mm ulcerated tumor, and the pathologic examination revealed a poorly differentiated adenocarcinoma invading to the serosa with lymph nodes metastases.
We reviewed the case of 21 Japanese patients with poorly differentiated adenocarcinoma of the duodenum and analyzed the clinicopathologic features.