Abstract
A 66-year-old woman was seen at our hospital because of a palpable left breast tumor. Although she was diagnosed as primary macrogloblinemia, she has been followed without therapy since there were no subjective symptoms. Result of aspiration cytology was class III b, and medullary carcinoma was suspected. Although we suspected breast cancer with close examination and performed operation, histopathological examination and immunohistological stainings revealed malignant lymphoma, non-Hodgkin type, diffuse, large B cell type. Since pancytopenia developed postoperatively we diagnosed the exacerbation of macrogloblinemia. Although she was treated with chemotherapy at another hospital, she died of pulmonary hemorrhage complicated with pulmonary mycosis on the 89th POD. We report a rare case of primary malignant lymphoma of the breast which supervened on primary macroglobulinemia with some bibliographical review.
