Abstract
A 75-year-old man was admitted to the hospital because of melena in November 2007. On gastrointestinal fiberscopy, a type 2 tumor was located in the gastric body. Endoscopic biopsy specimens from the tumor revealed gastric small cell carcinoma (SCC). Immunohistochemically, the component of SCC was positive for Chromogranin A. Computed tomographic (CT) scans showed no lymph node metastases or liver metastases. Distal gastrectomy with D1+α lymph node dissection and Billroth-I reconstruction was performed with the diagnosis of SCC {pT2 (MP), pN1, fStageII} in February 2008. The patient did not receive adjuvant chemotherapy because she had dementia after cerebral hemorrhage. Abdominal contrast-enhanced CT scan performed 4 months after the operation disclosed multiple hepatic metastases, and TS-1 regimen at a dose of 100mg daily was started, however, the patient died of progressed hepatic metastases 5 months after the operation.
SCC is a relatively rare entity and carries extremely poor prognosis. No standard therapies of the disease have been established as yet. In this paper we present this case of SCC of the stomach, together with a review of the domestic cases in terms of therapeutic methods and prognosis.
