Abstract
A 61-year-old male patient visited his private physician with the chief complaints of abdominal pain, anal pain and melena. The patient was referred to another physician with a diagnosis of rectal cancer with infiltration to the prostate. Since the patient was developing subileus, a double barrel sigmoid colostomy was made. Following a chemoradiotherapy (40Gy+UFT/UZEL), the patient was referred to us for a possible surgical intervention. However, a treatment with mFOLFOX6 was added in an effort to avoid a total pelvic exenteration. After 5 courses of the above treatment, the tumor showed a significant decrease of its size and MRI and EUS studies revealed no infiltration of the tumor to the prostate. Therefore, an abdominoperineal resection of the rectum was performed. There was severe adhesion between the prostate and the right anterior wall of the rectum, so the part of the prostate capsule and scar tissue was removed. In the resected specimen most of the adenocarcinoma disappeared and the histological evaluation of the treatment with chemoradiotherapy was assessed to be Grade 2. Some of the highly advanced cancer of the rectum often show high sensitivity for chemoradiotherapy.
