A rectal cancer case showing a variety of pathologies, including adenosquamous carcinoma

Abstract

A 66-year-old man visited our hospital with a chief complaint of anal hemorrhage. Endoscopic examinations of the lower gastrointestinal tract indicated carcinoma of the upper rectum, and a low anterior resection (D3) was carried out. The tumor was situated 10cm from the anal verge. The tumor perforated the mesorectum. Total mesorectal excision (TME) was performed on the anal canal and lateral lymphnode dissection was carried out. The histopathological diagnosis was adenosquamous carcinoma. In addition, there was an endocrine cell carcinoma with a rosette formation and various forms of organization were present. Theories about the genesis of adenosquamous carcinoma have been advocated. We report herein on the genesis and clinicopathological findings of adenosquamous carcinoma.