Abstract
We report a case of neuroendocrine carcinoma of the papilla Vater of the duodenum which is a rare entity. A 78-year-old woman was admitted to the hospital for close exprolation of liver dysfunction. Abdominal CT scan showed a contrast enhanced lesion, 1.5cm in diameter, in the pancreas head and intrahepatic bile duct dilatation. Immunohistological examination of endoscopic biopsy of the papilla Vater revealed CD56, synaptophysin and chromogranin A positive. Neuroendocrine tumor was thus diagnosed and we performed pyrolus preserved pancreaticoduodenectomy (PPPD) with lymph node dissection. The pathological diagnosis was well differentiated neuroendocrine carcinoma of the papilla Vater of the duodenum because the Ki67/MIB1 index was low and lymph node metastasis was found. She has been well and free from recurrence as of 16 months after the operation.
