A pseudomyxoma peritonei case demonstrating complete response with multidisciplinary treatment including modified folfox6 regimen

Abstract

A 75-year-old male with diffuse mucinous ascites underwent cytoreductive surgery including appendectomy. At laparotomy, cystadenocarcinoma was detected from the ascites and pathology revealed cystadenocarcinoma of the appendix with perforation. Pseudomyxoma peritonei caused by carcinoma of the appendix was diagnosed. The patient received a modified FOLFOX6 regimen postoperatively until the side-effect of peripheral neuropathy (Grade3) appeared after completion of 10 cycles. Despite this finding, a computed tomography (CT) scan revealed complete disappearance of ascites and no recurrence 6 months after discontinuation of chemotherapy. To date, the patient has been free of recurrence.