A case of adenoendocrine cell carcinoma of the gallbladder

Abstract

A 75-year-old man was seen due to right upper abdominal pain and fever. A diagnosis of cholecystitis and cholangitis was made. Abdominal ultrasonography showed a thick gallbladder wall with an irregular elevated lesion. Computed tomography showed stones in the common bile duct. PTCD was performed ; laparoscopic cholecystectomy and choledochotomy were performed after resolution of the inflammation. The tumor was located in the fundus of the gallbladder. On pathology, an adenoendocrine cell carcinoma was diagnosed. A diagnosis of gallbladder cancer was made, and a S4a, 5 bisegmentectomy of the liver with a regional lymph node resection (D2) was performed. The patient developed multiple metastases to the liver and lymph nodes 22 months after the operation and died 24 months after the operation. Since adenoendocrine cell carcinoma of the gallbladder is rare, we report this case along with the relevant literature.