Abstract
Mohs' paste is a histopathological fixative based on zinc chloride which is applled to perform chemosurgery of malignant tumors of the skin. We report our experience using this paste. Patient 1 was a female in her 60's who was emergently admitted with syncope due to a hemorrhage from her left breast cancer. Her breast cancer (11×6×11 cm) was diagnosed as stage IV (T4N3M1) and was unresectable. Therefore, chemotherapies and hormonal therapies were given. The hemorrhage from her cancer continued. Therefore, we used Mohs' paste, and hemostasis was achieved 24 hours later. The patient developed total necrosis of the cancer in one week, and the lesion fell off spontaneously about two weeks later. Patient 2 was a male in his 60's who had advanced lung cancer (squamous cell carcinoma, T2N2M1 stage IV). He developed an abdominal skin metastasis with a markedly pungent odor, and massive exudates that was painful ; this reduced his quality of life. After using Mohs' paste, the pungent odor and the exudates disappeared five days later ; the lesion was planarized about 4 weeks later, and the pain decreased.
