Abstract
We report a rare case of intestinal perforation associated with dialysis-related amyloidosis. A 61-year-old woman who had been receiving hemodialysis for 31 years required surgery for perforative peritonitis. A 1-cm perforation located in the ileum 20 cm proximal to the ileocecal junction was found. A partial resection of the ileum and an ileostomy were performed. On pathology, an amyloid deposit in a perivascular area of the submucosal layer was found ; Congo-red staining was positive. The patient was diagnosised as having dialysis-related amyloidosis. When panperitonitis is encountered in long-term hemodialysis patients, intestinal perforation due to dialysis-related amyloidosis should be considered in the differential diagnosis.