Abstract
A 60-year-old female with a tumor suspected to be a retroperitoneal fibrosarcoma underwent tumorectomy with left nephrectomy and left adrenal ectomy in October of 1988. CT scan showed local recurrence in the retroperitoneal space in November of 2003. Therefore, the tumor was removed with the spleen and transverse colon. The patient complained of dysphagia in May of 2008. CT scan showed that the tumor had spread from the retroperitoneal space to the mediastinum. We resected the tumor through a thoracoabdominal approach. The pathological diagnosis was a dedifferentiated liposarcoma. Retroperitoneal tumors have a variety of histopathological features. As a stem cell becomes differentiated, the retroperitoneal tumor may show a number of histological features. As there is little evidence of the effectiveness of various adjuvant treatments, such as chemotherapy and radiotherapy, aggressive resection should be carried out. We present a rare case with dedifferentiated retroperitoneal liposarcoma. This patient survived long-term with multiple resections.