Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A case of gastrointestinal stromal tumor of the stomach with multiple liver metastases surviving long-term with multimodal treatment
Hiroomi OGAWAIzumi TAKEYOSHIYutaka SUNOSEDaisuke YOSHINARIOsamu TOTSUKAHiroyuki TOYA
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Keywords: GIST, imatinib, stomach
JOURNAL FREE ACCESS

2011 Volume 72 Issue 3 Pages 663-669

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Abstract
A 54-year-old man had a left adrenal gland abnormality and underwent surgery with a preoperative diagnosis of left adrenal tumor based on an imaging study. The pathological examination revealed the tumor to be a gastrointestinal stromal tumor (GIST) growing out of the gastric wall.
He was diagnosed with multiple metastatic liver tumors 2 years and 2 months after the first surgery and underwent a partial hepatectomy. Due to the frequent recurrence of multiple liver metastases, he also underwent three radiofrequency ablations. As the period from treatment to recurrence became shorter, we started oral imatinib therapy, and he remained recurrence free for 6 years and 7 months after the first recurrence. Although imatinib administration is the first-choice therapy for recurrent GIST, one must consider active surgical treatment for resectable lesions, in particular for patients with a long period between their first treatment and recurrence.
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© 2011 Japan Surgical Association
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