Abstract
We report a case of adenosquamous cell carcinoma of the gallbladder which had a good prognosis after radical resection. A 69-year-old man was admitted with high fever and was initially diagnosed as having an acute cholecystitis and a liver abscess. Finally, the patient was diagnosed as having cancer of the gallbladder, based on CT scan and ultrasonography. The lumen of the gallbladder was filled with a tumor, and liver invasion was present. On blood tests, a high serum SCC level and inflammation was noted. Adenosquamous cell carcinoma was suspected. A radical resection involving cholecystectomy, hepatectomy of S4a + S5 subsegments and common bile duct resection were performed. On histopathology, an adenosquamous cell carcinoma of the gallbladder with massive liver invasion and regional lymphatic metastasis was diagnosed. The final residual tumor status was R0. The patient has survived recurrence-free for 69 months after radical resection without adjuvant therapy.