Abstract
Lymphoepithelial cysts (LEC) of the pancreas are non-neoplastic cystic lesions and are not candidates for surgery if the definite diagnosis is made preoperatively. However, these lesions are often resected because the differentiation from malignant diseases such as mucin-producing neoplasm is difficult. LEC of the pancreas, especially LEC with sebaceous differentiation, is rare.
In case 1, there was a well-circumscribed cystic tumor at the body and tail of the pancreas. We performed distal pancreatectomy without gaining definitive preoperative diagnosis.
In case 2, a well-defined cystic tumor with an inner portion comprised solid components was found at the pancreas tail. Judged from our experience with case 1, LEC was suspected during the operation. Tumor enucleation was thus performed to get the diagnosis of LEC. Histopathologically, the cyst wall was lined by squamous epithelium with sebaceous glands and surrounded by lymphoid tissue in both cases. They were subsequently diagnosed as LEC of the pancreas with sebaceous differentiation.
