A clinical study of surgical cases of entero-behçet's disease

Abstract

We studied surgical cases of entero-Behçet's disease experienced in our department during the past 10 years. A total of seven consecutive patients were enrolled in this study. An average age of them at the initial surgery was 55 years old. All patients were female. Their reasons for operations were perforation in two cases, stenosis in two, bleeding in two, unsuiTable candidate for medical treatment in two, and associated malignancy in one. These lesions were mainly located in the ileum, cecum, ascending colon, and stomach. The resected materials in all cases showed non-specific ulcer histopathologically. In all patients performed operations of the ileum and/or the colon, intestinal fistula was made, and some patients required multiple operations for anastomotic leakage or re-perforation. Six out of the seven patients experienced recurrence of the lesion or complications such as anastomotic leakage at the surgical anastomotic region involving the closed intestinal fistula or in the vicinity of the anastomosis.
Entero-Behçet's disease that can easily develop postoperative comlplications such as suture failure or recurrence of the lesion is a disorder that is difficult to treat. In order to control the progression of the disease as well as to minimize postoperative complications at the anastomotic region, early intervention of medical treatment would be important after surgery.