Abstract
We present a case with a giant retroperitoneal liposarcoma during pregnancy with 4 year survival after resection. A 30-year-old pregnant female at 12-weeks gestation was referred with a left-sided retroperitoneal tumor. Magnetic Resonance Imaging (MRI) showed a 30cm multilocular tumor along the left iliopsoas muscle. The tumor was resected using a retroperitoneal approach at 13-weeks gestation with meticulous intraoperative fetal monitoring, and revealed a low-grade myxoid liposarcoma on histopathological examination. She delivered a normal baby at 37-weeks gestation by cesarean section and was found to have no local recurrence at that time. Although she had a local recurrence 18 months after resection, the recurrent tumors were controlled by radiotherapy more for than 24 months and were resected 4 years after the fist resection because of re-growth. A retroperitoneal liposarcoma during pregnancy is extremely rare and is thought to carry a poor prognosis. This report emphasizes the importance of timing as well as the possibility of continuing the pregnancy, which requires a multidisciplinary team approach to achieve a successful outcome for the patient and her child.