Abstract
A 76-year-old man was admitted because of a high fever associated with shaking relating to chills. Abdominal ultrasonography and CT showed dilatation of the intrahepatic bile duct ; no tumor was detected. ERCP and MRCP revealed stricture of bile ducts (B2, B3, B4b) and dilatation of peripheral bile ducts. ENBD bile cytology was defined as class III b ; thus, the periductal infiltrating type of intrahepatic cholangiocarcinoma was strongly suspected. In addition, Strongyloides stercoralis filariform larvae were detected in the bile. A left hepatectomy was performed after treatment with Ivermectin (a vermifuge). The histological findings included superficial spreading adenocarcinoma in situ without invasive adenocarcinoma ; atypical biliary epithelium corresponding to BilIN-1-2 was also noted. We report this case of intrahepatic cholangiocarcinoma in situ associated with bile duct stricture that presented similarly to invasive cancer and appeared to be related to the presence of strongyloidiasis.
