Abstract
We report our experience with a giant pseudoangiomatous stromal hyperplasia (PASH) of the mammary gland in a 15-year-old girl. Her left breast was enlarged and an elastic soft lump was palpated. Ultrasonography showed a low echoic tumor with a clear boundary. Magnetic resonance imaging (MRI) revealed a poor contrast effect tumor on her left breast. A core needle biopsy was carried out under the suspicion of fibroadenoma or a phyllodes tumor. Pathological examination showed enlarged mammary stroma and sparse proliferation of spindle cells, and was diagnosed as PASH. Tumorectomy was performed, and the extracted specimen was covered with a thin coating, measuring 20×19 cm, and weighing 1.2 kg. A vessel-like space was observed in the mammary stroma upon histopathological findings and the inside of the space was coated by a layer of spindle cells. It was found to be CD34, αSMA positive, and CD31, PgR, ER negative upon immunohistological staining. Based on these findings, the patient was diagnosed with PASH of the mammary gland.
