Abstract
A 72-year-old woman who was diagnosed with psoriasis vulgaris 8 years ago consulted our hospital, complaining of exacerbation of skin rash and epigastric pain. An upper gastrointestinal endoscopy revealed an advanced gastric cancer (type 2) at the greater curvature of the antrum. A distal gastrectomy with D2 lymphatectomy was performed. Histological study showed poorly differentiated adenocarcinoma had invaded into the propria muscle of the stomach, with metastasis of regional lymph nodes. Skin rash disappeared 3 months after the operation, and treatment for psoriasis vulgaris was finished 7 months after the operation. In Japan, eight psoriasis vulgaris cases who were complicated with gastric cancer have been reported. In six cases, skin rash improved or disappeared after gastric resection. Gastroenterological cancer is likely to be one of the exacerbation factors of psoriasis vulgaris.
