Abstract
We present a case of a giant metastatic intraperitoneal tumor due to a malignant phyllodes tumor of the breast. A 53-year-old woman underwent mastectomy for a malignant phyllodes tumor of the breast. After 4 months, examinations revealed distant metastasis to the upper abdomen and lungs and local recurrence from the malignant phyllodes tumor. She underwent tumor resection for a metastatic peritoneal tumor and local recurrence. During the operation, the intraperitoneal tumor was found to have arisen from the retroperitoneum of the splenic hilum and the tail of the pancreas. The tumor was excised as thoroughly as possible. It weighed approximately 2,400 g. On pathological examination, the tumor proved to be a metastatic malignant phyllodes tumor of the breast. Chemotherapy with ifosfamide was started and sustained stable disease status for 5 months. However, the patient presented superior vena cava syndrome after 5 months. Although radiotherapy was carried out, she died 15 months after her first operation.
A standard treatment for metastatic malignant phyllodes tumors has not yet been established. Surgery is not a curative treatment but is useful for tumor debulking and improvement of the quality of life (QOL). In this case, tumor-debulking surgery and ifosfamide chemotherapy improved the QOL.
