Abstract
A 48-year-old woman developed a left breast mass. Mammography studies showed a rounded and micro-serrated mass ; breast cancer was suspected. The diagnosis of breast cancer was confirmed on core needle biopsy. Small hyperchromatic tumor cells arranged in a sheet, and both synaptophysin and chromogranin A were positive. Thus, small cell carcinoma was suspected. Neo-adjuvant chemotherapy involving a combination of CBDCA (carboplatin) and VP16 (etoposide) was given ; this treatment is used in lung small cell carcinoma. After chemotherapy, the tumor size decreased (partial response), and a breast-conserving surgery was done. Small cell carcinoma of the breast is rarely reported in the literature. We report our case, along with the relevant literature.
