Abstract
The subject was a 60-year-old postmenopausal woman who had undergone sigmoid colon resection and partial cystectomy for sigmoid colon cancer at 57 years of age. The histological type of the resected cancer was well-differentiated adenocarcinoma, with a mucinous carcinoma component. Two years 9 months after the initial surgery, a multilocular cystic mass extending 30 cm across the lower abdominal region appeared, for which a bilateral oophorectomy was performed. The right ovary was found to contain a giant cyst consisting of a smooth white capsule filled with a large quantity of brown mucus. Peritoneal dissemination of mucinous nodules was also observed. Histopathologically, the features were similar to those of ovarian mucinous cystadenocarcinoma. Cytokeratin (CK)7/CK20 staining, however, demonstrated a staining pattern similar to that of the previously resected colon cancer. Bilateral ovarian metastasis from sigmoid colon cancer was diagnosed following H.E. staining. A similar lesion was also observed in the morphologically normal left ovary. Primary mucinous carcinomas of the colon are rare. There have only been a few reports on ovarian metastasis with this cancer. While prognosis is poor for ovarian metastasis of colon cancer, there have been reports of long-term survival due to surgical resection, and consequently, we can expect to extend prognosis through active treatment of this condition.
