Abstract
A 68-year-old woman underwent surgical resection combined with local radiation and adjuvant chemotherapy for primary breast cancer. After one year, abdominal CT scan revealed a solitary liver metastasis. She underwent a right hepatectomy for the liver metastasis, which was HER2- positive, as was the primary tumor. Trastumab was administered as adjuvant chemotherapy. Three years after the first hepatectomy, an intrahepatic recurrence developed in the left lateral segment. Multiple chemotherapeutic regimens were given, but failed to reduce the tumor. Because the tumor recurrence was restricted to the liver, surgical resection was considered as a choice of treatment even though repeat hepatectomy is not a standard treatment for liver metastasis related to breast cancer. A left lateral segmentectomy of the liver was performed 5 years after the first hepatectomy. During the last three years the patient has been doing very well without requiring chemotherapy. Repeat hepatectomy may be a choice in patients with a single tumor and recurrence restricted to the liver.