Abstract
Case 1 : A 70-year-old man was admitted to receive neoadjuvant chemoradiotherapy (CRT) for esophageal cancer in our hospital. PICC was inserted in his left basilic vein to administer the chemotherapeutic agents. On day 29, we removed the PICC because of suspicion of catheter-related fever following neck phlegmone. Enhanced CT revealed thrombosis from his left jugular vein to the superior vena cava. Rapid anticoagulation therapy successfully improved the symptons. The thrombosis tended to shrink by continuous oral administration with warfarin. Case 2 : A 68-year-old woman had a scheduled operation for advanced gastric cancer. Due to undernutrition, a PICC was inserted in her left basilic vein for total parenteral nutrition. Three days later, we comfirmed thrombosis from her left jugular and subclavian to superior vena cava by CT. Then we removed the PICC and started anticoagulation thrapy. Seven days later, we comfirmed by CT that the thrombosis had improved moderately. It is suggested that PICC associated venous thrombosis can be related to long term PICC placement, undernutrition and dehydration in digestive surgery.
