Abstract
A 77-year-old man showed dilation of the main pancreatic duct on computed tomography (CT) screening performed before sigmoidectomy for sigmoid colon cancer. One year after the operation, he was found to have a pancreas head tumor with a size of 3 cm. Endoscopic retrograde cholangiopancr-eatography (ERCP) showed obstruction of the main pancreatic duct in the pancreas head. The patient was diagnosed with pancreatic cancer, and he underwent pancreaticoduodenectomy. Histological examination showed anaplastic cancer (spindle type), pStage III. Since the posterior retroperitoneal margin of the tumor was positive for cancer cells, Gemstabin administration was started. Colon cancer metastasis was diagnosed, and pulmonectomy of the right superior and mid-lobe was performed, after which the patient received S-1 for 8 months until he quit because of anorexia. The patient has not shown disease recurrence for 4 years after pancreaticoduodenectomy. Anaplastic carcinoma of the pancreas is a relatively rare aggressive pancreatic tumor. This is the first report of long-term survival in a case of spindle-cell-type anaplastic cancer. We suggest some hypotheses with the pathological and clinical features of this case, and we report the relevant bibliographic comments.
