Abstract
We report a case of Paget's disease of the nipple after breast-conserving surgery. The case involved a 64-year-old postmenopausal woman who had undergone breast-conserving surgery and sentinel lymph node biopsy with radiation therapy for ductal carcinoma in situ of the left breast (pTis pN0 M0 Stage 0) at another hospital in 2002. She noticed skin erosion of the left nipple and areola about 1.5 years after the breast-conserving treatment (BCT). She had been followed at the hospital with a diagnosis of dermatitis. Erosion of the nipple and areola had expanded in about 5 years after the BCT. Skin biopsy of the areola confirmed Paget's disease after BCT. She was referred to our hospital and left total mastectomy was performed for Paget's disease after BCT. Such a recurrence as Paget's disease of the nipple occurs after BCT like in this case is comparatively rare, but its clinical course can be observed during long-term follow-up period. Paget's disease of the nipple should be suspected whenever nipple changes appear after BCT for early diagnosis of recurrence.
