Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A case of angiosarcoma of the breast administered inetrleukin-2 for three years—report of a case
Norihiro HOKIMOTOTakeki SUGIMOTOTaku FUNAKOSHIMaho OGAWAKazuhiro HANAZAKI
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2012 Volume 73 Issue 4 Pages 786-791

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Abstract
A 27-year-old woman who had been aware of a left breast tumor for about one year visited the previous hospital because the tumor gradually increased. It was diagnosed as phyllodes tumor, and she was referred to our hospital. On physical examination, two well-defined tumors were palpable ; one was 7×6 cm in diameter in the BDE region and the other was 5×5 cm in diameter in the C region of the left breast. Phyllodes tumors were likely. We removed tumors two weeks later, when the tumors had rapidly increased and a new lesion appeared in the D region of the left breast. Moreover three other tumors 3 cm in maximum diameter were identified in A and C regions of the right breast. She underwent resection of three tumors in the left breast. All of them were pathologically diagnosed as angiosarcoma and surgical margins were positive. Thereafter she underwent left mastectomy and excisions of all tumors identified. Repeating surgical excisions of new lesions, we treated her with chemotherapy and interleukin-2. She died three years and four months after the initial surgery. We consider that repeated surgical excisions of skin metastases might elongate the survival duration because the final cause of her death was continuous bleeding from unresectable large skin metastases.
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© 2012 Japan Surgical Association
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