Abstract
We report a rare case of pancreatic metastasis from malignant melanoma. The patient was a 64-year-old woman who was diagnosed with right inguinal lymph node metastasis of malignant melanoma with unknown origin. The malignant melanoma was treated with systemic chemotherapy, but abdominal computed tomography (CT) scan revealed a tumor in the tail of the pancreas, 4 years and 2 months after the first diagnosis. We performed a distal pencreatectomy with splenectomy, and histopathological examination revealed the tumor to be a pancreatic lymph node metastasis of malignant melanoma with invasion to the pancreas. After the operation, there was peritoneal dissemination and lymph node recurrence, and those were also resected. She underwent systemic chemotherapy for liver and lung metastasis and survived for 4 years and 6 months. We recommend that a combination of surgical resection and systemic chemotherapy is effective for patients with metastatic tumor in the pancreas from malignant melanoma.
