Abstract
A 74-year-old man was admitted to our institution for treatment of a tumor in his upper abdomen. Endoscopy revealed a Borrmann type 3 tumor in the antrum. Biopsy of the tumor specimen showed moderately differentiated tubular adenocarcinoma. Therefore, distal gastrectomy and partial resection of the transeverse colon were performed. Pathological examination of the tumor revealed that the tumor was moderately differentiated tubular adenocarcinoma focus of the neuroendocrine carcinoma, which showed positive results for chromogranin A and synaptophysin in an immunohistological examination. Therefore, the patient underwent postoperative oral chemotherapy with TS-1 after being discharged and has remained free from recurrence. Here, we report a rare case of a patient with synchrous neuroendocrine cell carcinoma and moderately differentiated tubular adenocarcinoma of the stomach, and review the related literature.
