Abstract
The first case was a 77-year-old woman. She had upper abdominal pain, and imaging tests showed cholangiocellular carcinoma of intraductal growth type in the left lateral posterior segmental bile duct (B2). We performed a left hepatectomy, preserving the caudate lobe. The resected specimen showed a light yellow soft tumor measuring 35 mm. Histological examination showed the tumor was an intraductal papillary neoplasm of the bile duct (IPNB). It contained a lesion consisting of carcinoma in situ. The second case was a 65-year-old woman. She had a fever, and imaging tests showed a mucin-producing cholangiocarcinoma in the left lateral anterior segmental bile duct (B3). We performed a left hepatectomy, preserving the caudate lobe. There was light yellow mucus in the dilated B3. Histological examination showed IPNB in B3. Recently IPNB is recognized as the biliary counterpart of intraductal papillary mucinous neoplasm (IPMN) of the pancreas. We report these two cases of IPNB in B2 and B3, and review the relevant literature.
