Abstract
A 74-year-old man had surgery one year prior to resect a duodenal polyp at another hospital. Follow-up upper gastrointestinal endoscopy revealed an irregular elevated lesion in the second portion of the duodenum. On pathology of a biopsy specimen a diagnosis of well differentiated adenocarcinoma was made, and the patient was admitted to our hospital. Duodenal cancer was diagnosed, and a pylorus-preserving pancreaticoduodenectomy was performed. On histopathology of the resected specimen, a well differentiated adenocarcinoma primary located in the minor duodenal papilla was diagnosed. Therefore, a primary adenocarcinoma of the minor duodenal papilla was diagnosed. Currently, the patient is alive without recurrence for 3 months since surgery. Primary adenocarcinoma of the minor duodenal papilla is rare. Thus, we report this case with a review of the literature.