Abstract
A 25-year-old man was diagnosed as having Ehlers-Danlos syndrome when he was 5 years old due to the presence of developmental retardation, hyperextensibility of the skin and joints, and skin fragility. He was admitted because of anemia. Colonoscopy revealed a type-2 colon cancer in the sigmoid colon ; based on the pathology of the biopsy specimen, a well to moderately differentiated adenocarcinoma was diagnosed.
Sigmoidectomy with simultaneous anastomosis was performed. Anastomosis leakage occurred and was treated conservatively ; the patient was discharged 35 days after surgery. On pathology, an SS, N1, H0, P0, M0, Stage IIIa lesion was diagnosed. He was admitted with a bowel obstruction on 3 occassions. There has been no evidence of recurrence to date. EDS is a rare hereditary disease caused by a genetic connective tissue disorder. Patients with EDS show various manifestations, depending on the clinical type of EDS that they have. Appropriate operative procedures, perioperative care, and follow-up which address the particular features of the patient's disease are needed for EDS patients with colon cancer.
