Abstract
Hepatobiliary cystadenoma with ovarian-like stroma is a relatively rare cystic hepatic neoplasm that is prevalent in females. A 44-year-old woman was referred to our hospital because of a tumor (diameter, 2.5 cm) in the liver detected by ultrasonography at another hospital in 2003. She had been under observation because the tumor was diagnosed as a hemangioma. In 2007, the tumor increased to 7 cm in diameter. CT showed a multilocular, 78-mm cystic tumor in segment 4 of the liver, and ERCP showed that the tumor did not communicate with the intrahepatic bile duct. The serum levels of tumor markers were within normal ranges. Hepatobiliary cystadenoma or cystadenocarcinoma was diagnosed, and a left lobectomy was performed. The resected specimen contained the multilocular cystic tumor, but no recognizable solid lesion was found. Based on histopathology, hepatobiliary cystadenoma with ovarian-like stroma was diagnosed. Since a hepatobiliary cystadenoma may undergo malignant transformation and is difficult to distinguish from an adenocarcinoma before the operation, total excision of the tumor is recommended.
