Abstract
A naphylactoid purpura affected adults has been pointed out to be a possible dermadrome. We experienced a case of anaphylactoid purpura associated with rectal cancer.
A 65-year-old woman was admitted to our hospital for edema of the both legs, abdominal pain and hematuria. We also observed non-infiltrative purpura spots scattering on the legs. Skin biopsy demonstrated vasculitis with infiltration of polymorphonuclear cells into the vessel wall in dermis. Anaphylactoid purpura with kidney dysfunction (hematuria and urine protein of 1.9g per day) was thus diagnosed. In addition, colonoscopy revealed advanced rectal cancer. We assumed that the anapylactoid purpura was associated with the rectal cancer. We performed anterior resection with D3 lymph node dissection for rectal cancer. Pathology of the resected tumor, 30×20mm in diameter, demonstrated type 2, well differentiated adenocarcinoma, SS, N0 (0/12) , H0P0M0, and fStage II. Renal biopsy conducted after the surgery showed the presence of mesangial deposits of IgA and C3. Eruption disappeared completely and the kidney function remarkably improved after the surgery. Accordingly we concluded that anaphylactoid purpura was the dermadrome of the rectal cancer in our case.
