Abstract
A 74-year-old man who tested negative for various viral markers visited a local physician with a chief complaint of heaviness in the abdomen. He was referred to our hospital after a tumor was detected in the right lobe of the liver on abdominal ultrasound. Magnetic resonance imaging (MRI) showed a tumor lesion, 8 cm in size, in segments 6/5 (S6/5) of the liver. Dynamic imaging showed contrast enhancement in the arterial phase and washout in the portal venous phase within the tumor interior. Based on a diagnosis of hepatocellular carcinoma, subsegmental resention of S6 of the liver and partial resection of S5 of the liver were performed. The tumor had a well-defined capsule, and its interior contained necrotic matter. Histopathological findings included extensive necrosis of cells within the capsule, with no viable tumor cells. Sinusoidal supporting tissue was observed within the tumor interior, and the hepatocellular carcinoma was thought to have undergone complete spontaneous necrosis. In addition, no abnormal findings were observed in the background liver. This very rare case of complete spontaneous necrosis of hepatocellular carcinoma that occurred in normal liver is reported
