Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
Online ISSN : 1882-5133
Print ISSN : 1345-2843
ISSN-L : 1345-2843
Case Reports
A Case of Cardiac and Pulmonary Metastases of Hepatocellular Carcinoma with No Recurrence for Seven Years after a Radical Operation
Takahito MINAMI, Takamichi ISHII, Etsuro HATANO, Toshimi KAIDO, Sachiko MINAMIGUCHI, Shinji UEMOTO
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2013 Volume 74 Issue 10 Pages 2875-2878

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Abstract
The patient was in his eighties who had a 15 cm hepatocellular carcinoma (HCC) in the right lobe of the liver, and underwent right hepatectomy 7 years ago. The pathological study revealed poorly differentiated HCC with microvascular invasion. Although no recurrence was found during the 7 years after the operation, multiple tumors were detected in the myocardium of the right ventricle and the right lower lobe of the lung. Percutaneous biopsy obtained from the tumor of the right lung showed HCC cells. The tumor in the myocardium of the right ventricle was enhanced by gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) magnetic resonance imaging (MRI), thus suggesting cardiac metastasis of HCC. No recurrence was found in the liver. Therefore, he was diagnosed with lung and cardiac metastasis of HCC, and then treatment was started with sorafenib. However, because of erythema multiforme, sorafenib therapy was ceased and the treatment was shifted to palliative care. The metastasis of the HCC to the myocardium of the right ventricle is rare, and there are even fewer reports without hepatic recurrence. Herein, we reported this case with a review of the literature.
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© 2013 Japan Surgical Association
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