Abstract
A 71-year-old man was admitted to our hospital because of hypochondrial pain. Abdominal computed tomography (CT) and magnetic resonance cholangiopancreatography (MRCP) showed multiple cystic lesions in the pancreatic body and tail. The multilocular cyst in the pancreatic tail was 20 mm in diameter with an enhanced irregular shaped component, so that the malignant disease could not be refuted. We conducted a laparoscopic distal pancreatectomy with splenectomy for the definite diagnosis. There were no postoperative complications and he was discharged on the 14th day after surgery. Final pathological diagnosis of the cystic lesion in the pancreatic tail was a well-differentiated endocrine tumor (benign behavior). Laparoscopic distal pancreatectomy is a useful therapeutic choice for malignant boundary lesions of the pancreatic body and tail, as seen in this case.