Abstract
A 50-year-old woman who had bloody nipple discharge and was successfully treated with duct-lobular segmentectomy (DLS) using indocyanine green (ICG) fluorescence is reported. She had a mass that measured 1.0 cm in maximum diameter in the upper inner quadrant of her left breast. A definite diagnosis could not be obtained preoperatively with fine needle aspiration cytology, because her sister had died of breast cancer, the patient expected a solution as soon as possible. DLS was performed in order to confirm the diagnosis and treat the nipple discharge simultaneously. The mixture of indiogocarmine and ICG in a ratio of 9 : 1 was infused into the central duct from which the bloody discharge excreted. The ICG fluorescence was clearly observed and the target segment was determined precisely. Histopathological diagnosis was intraductal papilloma. There was no postoperative recurrence of bloody nipple discharge. DLS is useful for the diagnosis and treatment of nipple discharge, especially for patients with undetermined target lesions. ICG fluorescence imaging has the potential to be a more accurate determination method to target resection.