Abstract
A 37-year-old man had a history of eosinophilia and asthma. He was treated by the neighbourhood doctors for fever, stomachache, vomiting, and diarrhea with eosinophilia. Prednisolone (PSL) was prescribed because the symptoms persisted without improvement. Increasing abdominal pain was detected on day 7 after PSL initiation, and CT revealed free air in the abdominal cavity. He was taken to our hospital and an emergency operation was perfomed. An ileac perforation was found and multiple ulcerative lesions were detected in other parts of small intestine. Ileotomy and ileostomy were performed. Steroid pulse and cyclophosphamide combination therapy was administered after the operation. He was discharged on day 57 after the operation.